diff --git a/sdk/storage/Azure.Storage.Blobs/assets.json b/sdk/storage/Azure.Storage.Blobs/assets.json
index 46a74dc97b01..e0cc7497a2f2 100644
--- a/sdk/storage/Azure.Storage.Blobs/assets.json
+++ b/sdk/storage/Azure.Storage.Blobs/assets.json
@@ -2,5 +2,5 @@
   "AssetsRepo": "Azure/azure-sdk-assets",
   "AssetsRepoPrefixPath": "net",
   "TagPrefix": "net/storage/Azure.Storage.Blobs",
-  "Tag": "net/storage/Azure.Storage.Blobs_be75b1430c"
+  "Tag": "net/storage/Azure.Storage.Blobs_14eb1d6279"
 }
diff --git a/sdk/storage/Azure.Storage.Blobs/tests/BlobBaseClientTests.cs b/sdk/storage/Azure.Storage.Blobs/tests/BlobBaseClientTests.cs
index 14116ab039dd..25db387f24a9 100644
--- a/sdk/storage/Azure.Storage.Blobs/tests/BlobBaseClientTests.cs
+++ b/sdk/storage/Azure.Storage.Blobs/tests/BlobBaseClientTests.cs
@@ -5110,6 +5110,83 @@ await TestHelper.AssertExpectedExceptionAsync<RequestFailedException>(
                 e => Assert.AreEqual("BlobNotFound", e.ErrorCode));
         }
 
+        [RecordedTest]
+        public async Task SetMetadataAsync_Sort()
+        {
+            await using DisposingContainer test = await GetTestContainerAsync();
+            // Arrange
+            BlobBaseClient blob = await GetNewBlobClient(test.Container);
+            IDictionary<string, string> metadata = new Dictionary<string, string>() {
+                { "a0", "a" },
+                { "a1", "a" },
+                { "a2", "a" },
+                { "a3", "a" },
+                { "a4", "a" },
+                { "a5", "a" },
+                { "a6", "a" },
+                { "a7", "a" },
+                { "a8", "a" },
+                { "a9", "a" },
+                { "_", "a" },
+                { "_a", "a" },
+                { "a_", "a" },
+                { "__", "a" },
+                { "_a_", "a" },
+                { "b", "a" },
+                { "c", "a" },
+                { "y", "a" },
+                { "z", "z_" },
+                { "_z", "a" },
+                { "_F", "a" },
+                { "F", "a" },
+                { "F_", "a" },
+                { "_F_", "a" },
+                { "__F", "a" },
+                { "__a", "a" },
+                { "a__", "a" }
+             };
+
+            // Act
+            Response<BlobInfo> response = await blob.SetMetadataAsync(metadata);
+
+            // Assert
+
+            // Ensure that we grab the whole ETag value from the service without removing the quotes
+            Assert.AreEqual(response.Value.ETag.ToString(), $"\"{response.GetRawResponse().Headers.ETag}\"");
+
+            // Ensure the value has been correctly set by doing a GetProperties call
+            Response<BlobProperties> getPropertiesResponse = await blob.GetPropertiesAsync();
+            AssertDictionaryEquality(metadata, getPropertiesResponse.Value.Metadata);
+        }
+
+        [RecordedTest]
+        public async Task SetMetadataAsync_Sort_InvalidMetadata()
+        {
+            await using DisposingContainer test = await GetTestContainerAsync();
+            // Arrange
+            BlobBaseClient blob = await GetNewBlobClient(test.Container);
+            IDictionary<string, string> metadata = new Dictionary<string, string>() {
+                { "test", "val" },
+                { "test-", "val" },
+                { "test--", "val" },
+                { "test-_", "val" },
+                { "test_-", "val" },
+                { "test__", "val" },
+                { "test-a", "val" },
+                { "test-_A", "val" },
+                { "test_a", "val" },
+                { "test_Z", "val" },
+                { "test_a_", "val" },
+                { "test_a-", "val" },
+                { "test_a-_", "val" },
+             };
+
+            // Act
+            await TestHelper.AssertExpectedExceptionAsync<RequestFailedException>(
+                blob.SetMetadataAsync(metadata),
+                e => Assert.AreEqual(BlobErrorCode.InvalidMetadata.ToString(), e.ErrorCode));
+        }
+
         [RecordedTest]
         public async Task CreateSnapshotAsync()
         {
diff --git a/sdk/storage/Azure.Storage.Common/CHANGELOG.md b/sdk/storage/Azure.Storage.Common/CHANGELOG.md
index 47be03adb2b6..362318ed38bb 100644
--- a/sdk/storage/Azure.Storage.Common/CHANGELOG.md
+++ b/sdk/storage/Azure.Storage.Common/CHANGELOG.md
@@ -7,6 +7,7 @@
 ### Breaking Changes
 
 ### Bugs Fixed
+- Fixed \[BUG\] Azure Blob Storage Client SDK No Longer Supports Globalization Invariant Mode for Account Key Authentication #45052
 
 ### Other Changes
 
diff --git a/sdk/storage/Azure.Storage.Common/src/Shared/Constants.cs b/sdk/storage/Azure.Storage.Common/src/Shared/Constants.cs
index 48b4ca18cd54..6aebef8430e4 100644
--- a/sdk/storage/Azure.Storage.Common/src/Shared/Constants.cs
+++ b/sdk/storage/Azure.Storage.Common/src/Shared/Constants.cs
@@ -127,7 +127,6 @@ internal static class Constants
         public const string DisableExpectContinueHeaderEnvVar = "AZURE_STORAGE_DISABLE_EXPECT_CONTINUE_HEADER";
 
         public const string DefaultScope = "/.default";
-        public const string EnUsCulture = "en-US";
 
         /// <summary>
         /// Storage Connection String constant values.
diff --git a/sdk/storage/Azure.Storage.Common/src/Shared/StorageSharedKeyPipelinePolicy.cs b/sdk/storage/Azure.Storage.Common/src/Shared/StorageSharedKeyPipelinePolicy.cs
index fe787729a6ba..fddbb572c38f 100644
--- a/sdk/storage/Azure.Storage.Common/src/Shared/StorageSharedKeyPipelinePolicy.cs
+++ b/sdk/storage/Azure.Storage.Common/src/Shared/StorageSharedKeyPipelinePolicy.cs
@@ -23,21 +23,23 @@ internal sealed class StorageSharedKeyPipelinePolicy : HttpPipelineSynchronousPo
         private const bool IncludeXMsDate = true;
 
         /// <summary>
-        /// CultureInfo used to sort headers in the string to sign.
+        /// Shared key credentials used to sign requests
         /// </summary>
-        private static readonly CultureInfo s_cultureInfo = new CultureInfo(Constants.EnUsCulture, useUserOverride: false);
+        private readonly StorageSharedKeyCredential _credentials;
 
         /// <summary>
-        /// Shared key credentials used to sign requests
+        /// Used to sort headers to build the string to sign.
         /// </summary>
-        private readonly StorageSharedKeyCredential _credentials;
+        private static readonly HeaderComparer s_headerComparer = new HeaderComparer();
 
         /// <summary>
         /// Create a new SharedKeyPipelinePolicy
         /// </summary>
         /// <param name="credentials">SharedKeyCredentials to authenticate requests.</param>
         public StorageSharedKeyPipelinePolicy(StorageSharedKeyCredential credentials)
-            => _credentials = credentials;
+        {
+            _credentials = credentials;
+        }
 
         /// <summary>
         /// Sign the request using the shared key credentials.
@@ -117,10 +119,7 @@ private static void BuildCanonicalizedHeaders(StringBuilder stringBuilder, HttpM
                 }
             }
 
-            headers.Sort(static (x, y) =>
-            {;
-                return string.Compare(x.Name, y.Name, s_cultureInfo, CompareOptions.IgnoreSymbols);
-            });
+            headers.Sort(s_headerComparer);
 
             foreach (var header in headers)
             {
@@ -162,5 +161,102 @@ private void BuildCanonicalizedResource(StringBuilder stringBuilder, Uri resourc
                 }
             }
         }
+
+        internal class HeaderComparer : IComparer<HttpHeader>
+        {
+            private static readonly HeaderStringComparer s_headerComparer = new HeaderStringComparer();
+
+            public int Compare(HttpHeader x, HttpHeader y)
+            {
+                return s_headerComparer.Compare(x.Name, y.Name);
+            }
+        }
+
+        internal class HeaderStringComparer : IComparer<string>
+        {
+            private static readonly int[] s_table_lv0 =
+            {
+                0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,
+                0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,
+                0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x71c, 0x0,   0x71f, 0x721, 0x723, 0x725,
+                0x0,   0x0,   0x0,   0x72d, 0x803, 0x0,   0x0,   0x733, 0x0,   0xd03, 0xd1a, 0xd1c, 0xd1e,
+                0xd20, 0xd22, 0xd24, 0xd26, 0xd28, 0xd2a, 0x0,   0x0,   0x0,   0x0,   0x0,   0x0,   0x0,
+                0xe02, 0xe09, 0xe0a, 0xe1a, 0xe21, 0xe23, 0xe25, 0xe2c, 0xe32, 0xe35, 0xe36, 0xe48, 0xe51,
+                0xe70, 0xe7c, 0xe7e, 0xe89, 0xe8a, 0xe91, 0xe99, 0xe9f, 0xea2, 0xea4, 0xea6, 0xea7, 0xea9,
+                0x0,   0x0,   0x0,   0x743, 0x744, 0x748, 0xe02, 0xe09, 0xe0a, 0xe1a, 0xe21, 0xe23, 0xe25,
+                0xe2c, 0xe32, 0xe35, 0xe36, 0xe48, 0xe51, 0xe70, 0xe7c, 0xe7e, 0xe89, 0xe8a, 0xe91, 0xe99,
+                0xe9f, 0xea2, 0xea4, 0xea6, 0xea7, 0xea9, 0x0,   0x74c, 0x0,   0x750, 0x0,
+            };
+
+            private static readonly int[] s_table_lv2 =
+            {
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12,
+                0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x12, 0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+                0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,  0x0,
+            };
+
+            private static readonly int[] s_table_lv4 =
+            {
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x8012, 0x0, 0x0, 0x0, 0x0, 0x0, 0x8212, 0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+                0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0, 0x0, 0x0, 0x0, 0x0,    0x0, 0x0,
+            };
+
+            private static readonly int[][] s_tables = { s_table_lv0, s_table_lv2, s_table_lv4 };
+
+            public int Compare(string x, string y)
+            {
+                int currentLevel = 0;
+                int i = 0;
+                int j = 0;
+
+                while (currentLevel < s_tables.Length)
+                {
+                    if (currentLevel == s_tables.Length - 1 && i != j)
+                    {
+                        return j - i;
+                    }
+
+                    int weight1 = i < x.Length ? s_tables[currentLevel][x[i]] : 0x1;
+                    int weight2 = j < y.Length ? s_tables[currentLevel][y[j]] : 0x1;
+
+                    if (weight1 == 0x1 && weight2 == 0x1)
+                    {
+                        i = 0;
+                        j = 0;
+                        currentLevel++;
+                    }
+                    else if (weight1 == weight2)
+                    {
+                        i++;
+                        j++;
+                    }
+                    else if (weight1 == 0)
+                    {
+                        i++;
+                    }
+                    else if (weight2 == 0)
+                    {
+                        j++;
+                    }
+                    else
+                    {
+                         return weight1 - weight2;
+                    }
+                }
+
+                return 0;
+            }
+        }
     }
 }