diff --git a/INSTALL_MACOS.md b/INSTALL_MACOS.md
index 61ceef9fb8..fda193782b 100644
--- a/INSTALL_MACOS.md
+++ b/INSTALL_MACOS.md
@@ -355,32 +355,29 @@ config.pri:
  # copy and paste the following in a terminal
 cat > config.pri << EOF
 boost {
-  BOOST_VERSION = \$\$system("ls /opt/local/libexec/boost|sort|tail -1")
-  message("found boost \$\$BOOST_VERSION")
-  INCLUDEPATH += /opt/local/libexec/boost/\$\$BOOST_VERSION/include
-  LIBS += -L/opt/local/libexec/boost/\$\$BOOST_VERSION/lib -lboost_serialization-mt
+  LIBS += -lboost_serialization-mt
 }
 macx:openmp {
-  QMAKE_CC=/opt/local/bin/clang-mp-9.0
-  QMAKE_CXX=/opt/local/bin/clang++-mp-9.0
-  QMAKE_OBJECTIVE_CC=\$\$QMAKE_CC -stdlib=libc++
+  QMAKE_CC=/opt/local/bin/clang-mp-12
+  QMAKE_CXX=/opt/local/bin/clang++-mp-12
+  QMAKE_OBJECTIVE_CC=$$QMAKE_CC -stdlib=libc++
   QMAKE_LINK=\$\$QMAKE_CXX
 
-  INCLUDEPATH += /opt/local/include/libomp
-  LIBS += -L/opt/local/lib/libomp -liomp5
+  INCLUDEPATH += /opt/local/include /opt/local/include/libomp
+  LIBS += -L/opt/local/lib  -L/opt/local/lib/libomp -liomp5
   cc_setting.name = CC
-  cc_setting.value = /opt/local/bin/clang-mp-9.0
+  cc_setting.value = \$\$QMAKE_CC
   cxx_setting.name = CXX
-  cxx_setting.value = /opt/local/bin/clang++-mp-9.0
+  cxx_setting.value = \$\$QMAKE_CXX
   ld_setting.name = LD
-  ld_setting.value = /opt/local/bin/clang-mp-9.0
+  ld_setting.value = \$\$QMAKE_CC
   ldplusplus_setting.name = LDPLUSPLUS
-  ldplusplus_setting.value = /opt/local/bin/clang++-mp-7.0
+  ldplusplus_setting.value = \$\$QMAKE_CXX
   QMAKE_MAC_XCODE_SETTINGS += cc_setting cxx_setting ld_setting ldplusplus_setting
   QMAKE_FLAGS = "-B /usr/bin"
 
-  # clang (as of 5.0) does not yet support index-while-building functionality
-  # present in Xcode 9, and Xcode 9's clang does not yet support OpenMP
+  # clang (as of 12.0.1) does not yet support index-while-building functionality
+  # present in Xcode 9 and later, and Xcode's clang (as of 13.0) does not yet support OpenMP
   compiler_index_store_enable_setting.name = COMPILER_INDEX_STORE_ENABLE
   compiler_index_store_enable_setting.value = NO
   QMAKE_MAC_XCODE_SETTINGS += compiler_index_store_enable_setting
diff --git a/config-homebrew.pri b/config-homebrew.pri
new file mode 100644
index 0000000000..8028e108fe
--- /dev/null
+++ b/config-homebrew.pri
@@ -0,0 +1,32 @@
+boost: INCLUDEPATH += /usr/local/include
+boost: LIBS += -L/usr/local/lib -lboost_serialization-mt -lboost_thread-mt -lboost_system-mt
+expat: PKGCONFIG -= expat
+expat: INCLUDEPATH += /usr/local/opt/expat/include
+expat: LIBS += -L/usr/local/opt/expat/lib -lexpat
+openmp {
+  LIBS += -L/usr/local/opt/llvm@11/lib -lomp
+
+  cc_setting.name = CC
+  cc_setting.value = /usr/local/opt/llvm@11/bin/clang
+  cxx_setting.name = CXX
+  cxx_setting.value = /usr/local/opt/llvm@11/bin/clang++
+  ld_setting.name = LD
+  ld_setting.value = /usr/local/opt/llvm@11/bin/clang
+  ldxx_setting.name = LDPLUSPLUS
+  ldxx_setting.value = /usr/local/opt/llvm@11/bin/clang++
+  QMAKE_MAC_XCODE_SETTINGS += cc_setting cxx_setting ld_setting ldxx_setting
+  QMAKE_FLAGS = "-B /usr/bin"
+
+  # clang (as of 5.0) does not yet support index-while-building functionality
+  # present in Xcode 9, and Xcode 9's clang does not yet support OpenMP
+  compiler_index_store_enable_setting.name = COMPILER_INDEX_STORE_ENABLE
+  compiler_index_store_enable_setting.value = NO
+  QMAKE_MAC_XCODE_SETTINGS += compiler_index_store_enable_setting
+
+  # Xcode 9 compiles for 10.13 by default
+#  sdkroot_setting.name = SDKROOT
+#  sdkroot_setting.value = macosx10.14
+#  QMAKE_MAC_XCODE_SETTINGS += sdkroot_setting
+}
+#expat: INCLUDEPATH += /Users/devernay/Development/openfx/HostSupport/expat-2.1.0/lib
+#expat: LIBS += /Users/devernay/Development/openfx/HostSupport/Darwin-debug
diff --git a/config-macports.pri b/config-macports.pri
index 8393d1d922..0ac0754fb7 100644
--- a/config-macports.pri
+++ b/config-macports.pri
@@ -1,30 +1,27 @@
 boost {
-  BOOST_VERSION = $$system("grep 'default boost.version' /opt/local/var/macports/sources/rsync.macports.org/macports/release/tarballs/ports/_resources/port1.0/group/boost-1.0.tcl |awk '{ print $3 }'")
-  message("found boost $$BOOST_VERSION")
-  INCLUDEPATH += /opt/local/libexec/boost/$$BOOST_VERSION/include
-  LIBS += -L/opt/local/libexec/boost/$$BOOST_VERSION/lib -lboost_serialization-mt
+  LIBS += -lboost_serialization-mt
 }
 macx:openmp {
-  QMAKE_CC=/opt/local/bin/clang-mp-9.0
-  QMAKE_CXX=/opt/local/bin/clang++-mp-9.0
+  QMAKE_CC=/opt/local/bin/clang-mp-12
+  QMAKE_CXX=/opt/local/bin/clang++-mp-12
   QMAKE_OBJECTIVE_CC=$$QMAKE_CC -stdlib=libc++
   QMAKE_LINK=$$QMAKE_CXX
 
-  INCLUDEPATH += /opt/local/include/libomp
-  LIBS += -L/opt/local/lib/libomp -liomp5
+  INCLUDEPATH += /opt/local/include /opt/local/include/libomp
+  LIBS += -L/opt/local/lib  -L/opt/local/lib/libomp -liomp5
   cc_setting.name = CC
-  cc_setting.value = /opt/local/bin/clang-mp-9.0
+  cc_setting.value = $$QMAKE_CC
   cxx_setting.name = CXX
-  cxx_setting.value = /opt/local/bin/clang++-mp-9.0
+  cxx_setting.value = $$QMAKE_CXX
   ld_setting.name = LD
-  ld_setting.value = /opt/local/bin/clang-mp-9.0
+  ld_setting.value = $$QMAKE_CC
   ldplusplus_setting.name = LDPLUSPLUS
-  ldplusplus_setting.value = /opt/local/bin/clang++-mp-7.0
+  ldplusplus_setting.value = $$QMAKE_CXX
   QMAKE_MAC_XCODE_SETTINGS += cc_setting cxx_setting ld_setting ldplusplus_setting
   QMAKE_FLAGS = "-B /usr/bin"
 
-  # clang (as of 5.0) does not yet support index-while-building functionality
-  # present in Xcode 9, and Xcode 9's clang does not yet support OpenMP
+  # clang (as of 12.0.1) does not yet support index-while-building functionality
+  # present in Xcode 9 and later, and Xcode's clang (as of 13.0) does not yet support OpenMP
   compiler_index_store_enable_setting.name = COMPILER_INDEX_STORE_ENABLE
   compiler_index_store_enable_setting.value = NO
   QMAKE_MAC_XCODE_SETTINGS += compiler_index_store_enable_setting