diff --git a/CHANGES.md b/CHANGES.md
index 5c7733950aeba..bbf291ed8f418 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -62,8 +62,8 @@
 
 ## New Features / Improvements
 
-* Allow prebuilding large images when using `--prebuild_sdk_container_engine=cloud_build`, like images depending on `tensorflow` or `torch` ([#27023](https://github.com/apache/beam/pull/27023))
-* X feature added (Java/Python) ([#X](https://github.com/apache/beam/issues/X)).
+* Allow prebuilding large images when using `--prebuild_sdk_container_engine=cloud_build`, like images depending on `tensorflow` or `torch` ([#27023](https://github.com/apache/beam/pull/27023)).
+* Disabled `pip` cache when installing packages on the workers. This reduces the size of prebuilt Python container images ([#27035](https://github.com/apache/beam/pull/27035)).
 
 ## Breaking Changes
 
diff --git a/sdks/python/container/piputil.go b/sdks/python/container/piputil.go
index 03ac8325d6d06..a00e017445e30 100644
--- a/sdks/python/container/piputil.go
+++ b/sdks/python/container/piputil.go
@@ -37,14 +37,14 @@ func pipInstallRequirements(files []string, dir, name string) error {
 			// as possible PyPI downloads. In the first round the --find-links
 			// option will make sure that only things staged in the worker will be
 			// used without following their dependencies.
-			args := []string{"-m", "pip", "install", "-r", filepath.Join(dir, name), "--disable-pip-version-check", "--no-index", "--no-deps", "--find-links", dir}
+			args := []string{"-m", "pip", "install", "-r", filepath.Join(dir, name), "--no-cache-dir", "--disable-pip-version-check", "--no-index", "--no-deps", "--find-links", dir}
 			if err := execx.Execute("python", args...); err != nil {
 				fmt.Println("Some packages could not be installed solely from the requirements cache. Installing packages from PyPI.")
 			}
 			// The second install round opens up the search for packages on PyPI and
 			// also installs dependencies. The key is that if all the packages have
 			// been installed in the first round then this command will be a no-op.
-			args = []string{"-m", "pip", "install", "-r", filepath.Join(dir, name), "--disable-pip-version-check", "--find-links", dir}
+			args = []string{"-m", "pip", "install", "-r", filepath.Join(dir, name), "--no-cache-dir", "--disable-pip-version-check", "--find-links", dir}
 			return execx.Execute("python", args...)
 		}
 	}
@@ -76,18 +76,18 @@ func pipInstallPackage(files []string, dir, name string, force, optional bool, e
 				// installed version will match the package specified, the package itself
 				// will not be reinstalled, but its dependencies will now be resolved and
 				// installed if necessary.  This achieves our goal outlined above.
-				args := []string{"-m", "pip", "install", "--disable-pip-version-check", "--upgrade", "--force-reinstall", "--no-deps",
+				args := []string{"-m", "pip", "install", "--no-cache-dir", "--disable-pip-version-check", "--upgrade", "--force-reinstall", "--no-deps",
 					filepath.Join(dir, packageSpec)}
 				err := execx.Execute("python", args...)
 				if err != nil {
 					return err
 				}
-				args = []string{"-m", "pip", "install", "--disable-pip-version-check", filepath.Join(dir, packageSpec)}
+				args = []string{"-m", "pip", "install", "--no-cache-dir", "--disable-pip-version-check", filepath.Join(dir, packageSpec)}
 				return execx.Execute("python", args...)
 			}
 
 			// Case when we do not perform a forced reinstall.
-			args := []string{"-m", "pip", "install", "--disable-pip-version-check", filepath.Join(dir, packageSpec)}
+			args := []string{"-m", "pip", "install", "--no-cache-dir", "--disable-pip-version-check", filepath.Join(dir, packageSpec)}
 			return execx.Execute("python", args...)
 		}
 	}