diff --git a/scripts/react_native_pods.rb b/scripts/react_native_pods.rb
index 4386c9c970451c..3c6a21eacc81de 100644
--- a/scripts/react_native_pods.rb
+++ b/scripts/react_native_pods.rb
@@ -16,6 +16,13 @@ def use_react_native! (options={})
   # Include Hermes dependencies
   hermes_enabled = options[:hermes_enabled] ||= false
 
+  if `/usr/sbin/sysctl -n hw.optional.arm64 2>&1`.to_i == 1 && !RUBY_PLATFORM.start_with?('arm64')
+    Pod::UI.warn 'Do not use "pod install" from inside Rosetta2 (x86_64 emulation on arm64).'
+    Pod::UI.warn ' - Emulated x86_64 is slower than native arm64'
+    Pod::UI.warn ' - May result in mixed architectures in rubygems (eg: ffi_c.bundle files may be x86_64 with an arm64 interpreter)'
+    Pod::UI.warn 'Run "env /usr/bin/arch -arm64 /bin/bash --login" then try again.'
+  end
+
   # The Pods which should be included in all projects
   pod 'FBLazyVector', :path => "#{prefix}/Libraries/FBLazyVector"
   pod 'FBReactNativeSpec', :path => "#{prefix}/React/FBReactNativeSpec"