diff --git a/ReactAndroid/hermes-engine/build.gradle b/ReactAndroid/hermes-engine/build.gradle
index 4c10ddf56ba819..551c663775c3b5 100644
--- a/ReactAndroid/hermes-engine/build.gradle
+++ b/ReactAndroid/hermes-engine/build.gradle
@@ -174,7 +174,6 @@ android {
         release {
             externalNativeBuild {
                 cmake {
-                    arguments "-DHERMES_ENABLE_DEBUGGER=False"
                     arguments "-DCMAKE_BUILD_TYPE=MinSizeRel"
                 }
             }
diff --git a/ReactCommon/hermes/React-hermes.podspec b/ReactCommon/hermes/React-hermes.podspec
index 96bb1d0e152f62..a4e5ac4d6c339b 100644
--- a/ReactCommon/hermes/React-hermes.podspec
+++ b/ReactCommon/hermes/React-hermes.podspec
@@ -42,7 +42,7 @@ Pod::Spec.new do |s|
   s.pod_target_xcconfig    = {
                                "HEADER_SEARCH_PATHS" => "\"${PODS_ROOT}/hermes-engine/destroot/include\" \"$(PODS_TARGET_SRCROOT)/..\" \"$(PODS_ROOT)/boost\" \"$(PODS_ROOT)/RCT-Folly\" \"$(PODS_ROOT)/DoubleConversion\" \"$(PODS_ROOT)/libevent/include\"",
                                "CLANG_CXX_LANGUAGE_STANDARD" => "c++17"
-                             }.merge!(build_type == :debug ? { "GCC_PREPROCESSOR_DEFINITIONS" => "HERMES_ENABLE_DEBUGGER=1" } : {})
+                             }
   s.header_dir             = "reacthermes"
   s.dependency "React-cxxreact", version
   s.dependency "React-jsiexecutor", version
diff --git a/ReactCommon/hermes/executor/CMakeLists.txt b/ReactCommon/hermes/executor/CMakeLists.txt
index e10d5f2a14f7fa..de74c65daea888 100644
--- a/ReactCommon/hermes/executor/CMakeLists.txt
+++ b/ReactCommon/hermes/executor/CMakeLists.txt
@@ -19,7 +19,6 @@ target_link_libraries(hermes_executor_common
         jsireact
         hermes-engine::libhermes
         jsi
-        debug
         hermes_inspector
 )
 
diff --git a/ReactCommon/hermes/executor/HermesExecutorFactory.cpp b/ReactCommon/hermes/executor/HermesExecutorFactory.cpp
index 500eac9340a6fb..ef8bcae5932595 100644
--- a/ReactCommon/hermes/executor/HermesExecutorFactory.cpp
+++ b/ReactCommon/hermes/executor/HermesExecutorFactory.cpp
@@ -14,10 +14,8 @@
 #include <hermes/hermes.h>
 #include <jsi/decorator.h>
 
-#ifdef HERMES_ENABLE_DEBUGGER
 #include <hermes/inspector/RuntimeAdapter.h>
 #include <hermes/inspector/chrome/Registration.h>
-#endif
 
 #include "JSITracing.h"
 
@@ -35,8 +33,6 @@ std::unique_ptr<HermesRuntime> makeHermesRuntimeSystraced(
   return hermes::makeHermesRuntime(runtimeConfig);
 }
 
-#ifdef HERMES_ENABLE_DEBUGGER
-
 class HermesExecutorRuntimeAdapter
     : public facebook::hermes::inspector::RuntimeAdapter {
  public:
@@ -67,8 +63,6 @@ class HermesExecutorRuntimeAdapter
   std::shared_ptr<MessageQueueThread> thread_;
 };
 
-#endif
-
 struct ReentrancyCheck {
 // This is effectively a very subtle and complex assert, so only
 // include it in builds which would include asserts.
@@ -152,7 +146,6 @@ class DecoratedRuntime : public jsi::WithRuntimeDecorator<ReentrancyCheck> {
       const std::string &debuggerName)
       : jsi::WithRuntimeDecorator<ReentrancyCheck>(*runtime, reentrancyCheck_),
         runtime_(std::move(runtime)) {
-#ifdef HERMES_ENABLE_DEBUGGER
     enableDebugger_ = enableDebugger;
     if (enableDebugger_) {
       std::shared_ptr<HermesRuntime> rt(runtime_, &hermesRuntime);
@@ -161,15 +154,12 @@ class DecoratedRuntime : public jsi::WithRuntimeDecorator<ReentrancyCheck> {
       debugToken_ = facebook::hermes::inspector::chrome::enableDebugging(
           std::move(adapter), debuggerName);
     }
-#endif
   }
 
   ~DecoratedRuntime() {
-#ifdef HERMES_ENABLE_DEBUGGER
     if (enableDebugger_) {
       facebook::hermes::inspector::chrome::disableDebugging(debugToken_);
     }
-#endif
   }
 
  private:
@@ -182,10 +172,8 @@ class DecoratedRuntime : public jsi::WithRuntimeDecorator<ReentrancyCheck> {
 
   std::shared_ptr<Runtime> runtime_;
   ReentrancyCheck reentrancyCheck_;
-#ifdef HERMES_ENABLE_DEBUGGER
   bool enableDebugger_;
   facebook::hermes::inspector::chrome::DebugSessionToken debugToken_;
-#endif
 };
 
 } // namespace
diff --git a/ReactCommon/hermes/inspector/CMakeLists.txt b/ReactCommon/hermes/inspector/CMakeLists.txt
index ceec7dc1e63618..3dc0fba5de232d 100644
--- a/ReactCommon/hermes/inspector/CMakeLists.txt
+++ b/ReactCommon/hermes/inspector/CMakeLists.txt
@@ -15,7 +15,6 @@ add_library(hermes_inspector
 target_compile_options(
         hermes_inspector
         PRIVATE
-        -DHERMES_ENABLE_DEBUGGER=1
         -DHERMES_INSPECTOR_FOLLY_KLUDGE=1
         -std=c++17
         -fexceptions