diff --git a/Libraries/Animated/__tests__/Animated-web-test.js b/Libraries/Animated/__tests__/Animated-web-test.js
new file mode 100644
index 00000000000000..2fccade525c107
--- /dev/null
+++ b/Libraries/Animated/__tests__/Animated-web-test.js
@@ -0,0 +1,198 @@
+/**
+ * Copyright (c) Meta Platforms, Inc. and affiliates.
+ *
+ * This source code is licensed under the MIT license found in the
+ * LICENSE file in the root directory of this source tree.
+ *
+ * @format
+ * @oncall react_native
+ */
+
+const StyleSheet = require('../../StyleSheet/StyleSheet');
+let Animated = require('../Animated').default;
+let AnimatedProps = require('../nodes/AnimatedProps').default;
+
+jest.mock('../../Utilities/Platform', () => {
+  return {OS: 'web'};
+});
+
+describe('Animated tests', () => {
+  beforeEach(() => {
+    jest.resetModules();
+  });
+
+  describe('Animated', () => {
+    it('works end to end', () => {
+      const anim = new Animated.Value(0);
+      const translateAnim = anim.interpolate({
+        inputRange: [0, 1],
+        outputRange: [100, 200],
+      });
+
+      const callback = jest.fn();
+
+      const node = new AnimatedProps(
+        {
+          style: {
+            backgroundColor: 'red',
+            opacity: anim,
+            transform: [
+              {
+                translate: [translateAnim, translateAnim],
+              },
+              {
+                translateX: translateAnim,
+              },
+              {scale: anim},
+            ],
+            shadowOffset: {
+              width: anim,
+              height: anim,
+            },
+          },
+        },
+        callback,
+      );
+
+      expect(node.__getValue()).toEqual({
+        style: [
+          {
+            backgroundColor: 'red',
+            opacity: anim,
+            shadowOffset: {
+              width: anim,
+              height: anim,
+            },
+            transform: [
+              {translate: [translateAnim, translateAnim]},
+              {translateX: translateAnim},
+              {scale: anim},
+            ],
+          },
+          {
+            opacity: 0,
+            transform: [{translate: [100, 100]}, {translateX: 100}, {scale: 0}],
+            shadowOffset: {
+              width: 0,
+              height: 0,
+            },
+          },
+        ],
+      });
+
+      expect(anim.__getChildren().length).toBe(0);
+
+      node.__attach();
+
+      expect(anim.__getChildren().length).toBe(3);
+
+      anim.setValue(0.5);
+
+      expect(callback).toBeCalled();
+
+      expect(node.__getValue()).toEqual({
+        style: [
+          {
+            backgroundColor: 'red',
+            opacity: anim,
+            shadowOffset: {
+              width: anim,
+              height: anim,
+            },
+            transform: [
+              {translate: [translateAnim, translateAnim]},
+              {translateX: translateAnim},
+              {scale: anim},
+            ],
+          },
+          {
+            opacity: 0.5,
+            transform: [
+              {translate: [150, 150]},
+              {translateX: 150},
+              {scale: 0.5},
+            ],
+            shadowOffset: {
+              width: 0.5,
+              height: 0.5,
+            },
+          },
+        ],
+      });
+
+      node.__detach();
+      expect(anim.__getChildren().length).toBe(0);
+
+      anim.setValue(1);
+      expect(callback.mock.calls.length).toBe(1);
+    });
+
+    /**
+     * The behavior matters when the input style is a mix of values
+     * from StyleSheet.create and an inline style with an animation
+     */
+    it('does not discard initial style', () => {
+      const value1 = new Animated.Value(1);
+      const scale = value1.interpolate({
+        inputRange: [0, 1],
+        outputRange: [1, 2],
+      });
+      const callback = jest.fn();
+      const node = new AnimatedProps(
+        {
+          style: [
+            styles.red,
+            {
+              transform: [
+                {
+                  scale,
+                },
+              ],
+            },
+          ],
+        },
+        callback,
+      );
+
+      expect(node.__getValue()).toEqual({
+        style: [
+          [
+            styles.red,
+            {
+              transform: [{scale}],
+            },
+          ],
+          {
+            transform: [{scale: 2}],
+          },
+        ],
+      });
+
+      node.__attach();
+      expect(callback.mock.calls.length).toBe(0);
+      value1.setValue(0.5);
+      expect(callback.mock.calls.length).toBe(1);
+      expect(node.__getValue()).toEqual({
+        style: [
+          [
+            styles.red,
+            {
+              transform: [{scale}],
+            },
+          ],
+          {
+            transform: [{scale: 1.5}],
+          },
+        ],
+      });
+
+      node.__detach();
+    });
+  });
+});
+
+const styles = StyleSheet.create({
+  red: {
+    backgroundColor: 'red',
+  },
+});
diff --git a/Libraries/Animated/nodes/AnimatedStyle.js b/Libraries/Animated/nodes/AnimatedStyle.js
index 7cb11bb1b55679..31291968f16e15 100644
--- a/Libraries/Animated/nodes/AnimatedStyle.js
+++ b/Libraries/Animated/nodes/AnimatedStyle.js
@@ -13,24 +13,52 @@
 import type {PlatformConfig} from '../AnimatedPlatformConfig';
 
 import flattenStyle from '../../StyleSheet/flattenStyle';
+import Platform from '../../Utilities/Platform';
 import NativeAnimatedHelper from '../NativeAnimatedHelper';
 import AnimatedNode from './AnimatedNode';
 import AnimatedTransform from './AnimatedTransform';
 import AnimatedWithChildren from './AnimatedWithChildren';
 
+function createAnimatedStyle(inputStyle: any): Object {
+  const style = flattenStyle(inputStyle);
+  const animatedStyles: any = {};
+  for (const key in style) {
+    const value = style[key];
+    if (key === 'transform') {
+      animatedStyles[key] = new AnimatedTransform(value);
+    } else if (value instanceof AnimatedNode) {
+      animatedStyles[key] = value;
+    } else if (value && !Array.isArray(value) && typeof value === 'object') {
+      animatedStyles[key] = createAnimatedStyle(value);
+    }
+  }
+  return animatedStyles;
+}
+
+function createStyleWithAnimatedTransform(inputStyle: any): Object {
+  let style = flattenStyle(inputStyle) || ({}: {[string]: any});
+
+  if (style.transform) {
+    style = {
+      ...style,
+      transform: new AnimatedTransform(style.transform),
+    };
+  }
+  return style;
+}
+
 export default class AnimatedStyle extends AnimatedWithChildren {
+  _inputStyle: any;
   _style: Object;
 
   constructor(style: any) {
     super();
-    style = flattenStyle(style) || ({}: {[string]: any});
-    if (style.transform) {
-      style = {
-        ...style,
-        transform: new AnimatedTransform(style.transform),
-      };
+    if (Platform.OS === 'web') {
+      this._inputStyle = style;
+      this._style = createAnimatedStyle(style);
+    } else {
+      this._style = createStyleWithAnimatedTransform(style);
     }
-    this._style = style;
   }
 
   // Recursively get values for nested styles (like iOS's shadowOffset)
@@ -50,7 +78,11 @@ export default class AnimatedStyle extends AnimatedWithChildren {
     return updatedStyle;
   }
 
-  __getValue(): Object {
+  __getValue(): Object | Array<Object> {
+    if (Platform.OS === 'web') {
+      return [this._inputStyle, this._walkStyleAndGetValues(this._style)];
+    }
+
     return this._walkStyleAndGetValues(this._style);
   }