diff --git a/src/test/validation_chainstate_tests.cpp b/src/test/validation_chainstate_tests.cpp
index 4be568ab47d7d..1beef5cf04bef 100644
--- a/src/test/validation_chainstate_tests.cpp
+++ b/src/test/validation_chainstate_tests.cpp
@@ -43,6 +43,7 @@ BOOST_AUTO_TEST_CASE(validation_chainstate_resize_caches)
     c1.InitCoinsDB(
         /*cache_size_bytes=*/1 << 23, /*in_memory=*/true, /*should_wipe=*/false);
     WITH_LOCK(::cs_main, c1.InitCoinsCache(1 << 23));
+    BOOST_REQUIRE(c1.LoadGenesisBlock()); // Need at least one block loaded to be able to flush caches
 
     // Add a coin to the in-memory cache, upsize once, then downsize.
     {