diff --git a/src/tools/compiletest/src/runtest.rs b/src/tools/compiletest/src/runtest.rs
index 27a8079d893fa..61211a7d67538 100644
--- a/src/tools/compiletest/src/runtest.rs
+++ b/src/tools/compiletest/src/runtest.rs
@@ -2503,8 +2503,11 @@ impl<'test> TestCx<'test> {
                 // overridden by `compile-flags`.
                 rustc.arg("-Copt-level=2");
             }
-            RunPassValgrind | Pretty | DebugInfo | Codegen | Rustdoc | RustdocJson | RunMake
-            | CodegenUnits | JsDocTest | Assembly => {
+            Assembly | Codegen => {
+                rustc.arg("-Cdebug-assertions=no");
+            }
+            RunPassValgrind | Pretty | DebugInfo | Rustdoc | RustdocJson | RunMake
+            | CodegenUnits | JsDocTest => {
                 // do not use JSON output
             }
         }
diff --git a/tests/assembly/option-nonzero-eq.rs b/tests/assembly/option-nonzero-eq.rs
index d6ec586d938b0..b04cf63fd7837 100644
--- a/tests/assembly/option-nonzero-eq.rs
+++ b/tests/assembly/option-nonzero-eq.rs
@@ -5,7 +5,6 @@
 //@ compile-flags: --crate-type=lib -O -C llvm-args=-x86-asm-syntax=intel
 //@ only-x86_64
 //@ ignore-sgx
-//@ ignore-debug
 
 use std::cmp::Ordering;
 
diff --git a/tests/assembly/slice-is_ascii.rs b/tests/assembly/slice-is_ascii.rs
index 0b7643952149c..3a050347d8981 100644
--- a/tests/assembly/slice-is_ascii.rs
+++ b/tests/assembly/slice-is_ascii.rs
@@ -5,7 +5,6 @@
 //@ compile-flags: --crate-type=lib -O -C llvm-args=-x86-asm-syntax=intel
 //@ only-x86_64
 //@ ignore-sgx
-//@ ignore-debug
 
 #![feature(str_internals)]
 
diff --git a/tests/assembly/static-relocation-model.rs b/tests/assembly/static-relocation-model.rs
index 975818bf94fb0..50527b8534513 100644
--- a/tests/assembly/static-relocation-model.rs
+++ b/tests/assembly/static-relocation-model.rs
@@ -6,7 +6,6 @@
 //@ [A64] needs-llvm-components: aarch64
 //@ [ppc64le] compile-flags: --target powerpc64le-unknown-linux-gnu -Crelocation-model=static
 //@ [ppc64le] needs-llvm-components: powerpc
-//@ ignore-debug: alignment checks insert panics that we don't have a lang item for
 
 #![feature(no_core, lang_items)]
 #![no_core]
diff --git a/tests/codegen/align-offset.rs b/tests/codegen/align-offset.rs
index 9819dc209668e..15b11f413cb56 100644
--- a/tests/codegen/align-offset.rs
+++ b/tests/codegen/align-offset.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug (debug assertions in `slice::from_raw_parts` block optimizations)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/array-map.rs b/tests/codegen/array-map.rs
index b356f8f33f9f1..743a15989f78e 100644
--- a/tests/codegen/array-map.rs
+++ b/tests/codegen/array-map.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -C opt-level=3 -C target-cpu=x86-64-v3
 //@ only-x86_64
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/ascii-char.rs b/tests/codegen/ascii-char.rs
index 30f285096ed8d..fab9f8632fcad 100644
--- a/tests/codegen/ascii-char.rs
+++ b/tests/codegen/ascii-char.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -C opt-level=1
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 #![feature(ascii_char)]
diff --git a/tests/codegen/binary-search-index-no-bound-check.rs b/tests/codegen/binary-search-index-no-bound-check.rs
index d2627d67142f1..96f6bb54b3fe0 100644
--- a/tests/codegen/binary-search-index-no-bound-check.rs
+++ b/tests/codegen/binary-search-index-no-bound-check.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 #![crate_type = "lib"]
 
 // Make sure no bounds checks are emitted when slicing or indexing
diff --git a/tests/codegen/infallible-unwrap-in-opt-z.rs b/tests/codegen/infallible-unwrap-in-opt-z.rs
index cbcba03ad0a98..3756fafe3840c 100644
--- a/tests/codegen/infallible-unwrap-in-opt-z.rs
+++ b/tests/codegen/infallible-unwrap-in-opt-z.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -C opt-level=z --edition=2021
-//@ ignore-debug
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issue-97217.rs b/tests/codegen/issue-97217.rs
index 93dd1228ce123..a0dfff2ef2eb9 100644
--- a/tests/codegen/issue-97217.rs
+++ b/tests/codegen/issue-97217.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -C opt-level=3
-//@ ignore-debug: the debug assertions get in the way
 //@ min-llvm-version: 17.0.2
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-101082.rs b/tests/codegen/issues/issue-101082.rs
index 7c96f9a34f8cb..550d267a98fa2 100644
--- a/tests/codegen/issues/issue-101082.rs
+++ b/tests/codegen/issues/issue-101082.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-101814.rs b/tests/codegen/issues/issue-101814.rs
index 6175d80c9cde1..e3843e9edb0bd 100644
--- a/tests/codegen/issues/issue-101814.rs
+++ b/tests/codegen/issues/issue-101814.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-106369.rs b/tests/codegen/issues/issue-106369.rs
index 5120c5f4e4903..fd375e4e60584 100644
--- a/tests/codegen/issues/issue-106369.rs
+++ b/tests/codegen/issues/issue-106369.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-116878.rs b/tests/codegen/issues/issue-116878.rs
index 2c561d7be799b..a09fac42c0182 100644
--- a/tests/codegen/issues/issue-116878.rs
+++ b/tests/codegen/issues/issue-116878.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 #![crate_type = "lib"]
 
 /// Make sure no bounds checks are emitted after a `get_unchecked`.
diff --git a/tests/codegen/issues/issue-37945.rs b/tests/codegen/issues/issue-37945.rs
index 3f750157a8182..756a75e2f0ed3 100644
--- a/tests/codegen/issues/issue-37945.rs
+++ b/tests/codegen/issues/issue-37945.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O -Zmerge-functions=disabled
 //@ ignore-32bit LLVM has a bug with them
-//@ ignore-debug
 
 // Check that LLVM understands that `Iter` pointer is not null. Issue #37945.
 
diff --git a/tests/codegen/issues/issue-45222.rs b/tests/codegen/issues/issue-45222.rs
index 8fa9d87f4970f..d2c1ba421c45e 100644
--- a/tests/codegen/issues/issue-45222.rs
+++ b/tests/codegen/issues/issue-45222.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-45466.rs b/tests/codegen/issues/issue-45466.rs
index 165bc3ca41126..fc714247dfb6d 100644
--- a/tests/codegen/issues/issue-45466.rs
+++ b/tests/codegen/issues/issue-45466.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type="rlib"]
 
diff --git a/tests/codegen/issues/issue-45964-bounds-check-slice-pos.rs b/tests/codegen/issues/issue-45964-bounds-check-slice-pos.rs
index c9bc7fc316e94..b7568bea4d0a3 100644
--- a/tests/codegen/issues/issue-45964-bounds-check-slice-pos.rs
+++ b/tests/codegen/issues/issue-45964-bounds-check-slice-pos.rs
@@ -2,7 +2,6 @@
 // prevent optimizing away bounds checks
 
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type="rlib"]
 
diff --git a/tests/codegen/issues/issue-69101-bounds-check.rs b/tests/codegen/issues/issue-69101-bounds-check.rs
index f96a8e9da4b4e..c014a1c1b1d43 100644
--- a/tests/codegen/issues/issue-69101-bounds-check.rs
+++ b/tests/codegen/issues/issue-69101-bounds-check.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 #![crate_type = "lib"]
 
 // Make sure no bounds checks are emitted in the loop when upfront slicing
diff --git a/tests/codegen/issues/issue-73258.rs b/tests/codegen/issues/issue-73258.rs
index bc71e15a41fe2..48f14fe2dfe3e 100644
--- a/tests/codegen/issues/issue-73258.rs
+++ b/tests/codegen/issues/issue-73258.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/issues/issue-73396-bounds-check-after-position.rs b/tests/codegen/issues/issue-73396-bounds-check-after-position.rs
index db91a85474d2b..ef4538ac84e1b 100644
--- a/tests/codegen/issues/issue-73396-bounds-check-after-position.rs
+++ b/tests/codegen/issues/issue-73396-bounds-check-after-position.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 #![crate_type = "lib"]
 
 // Make sure no bounds checks are emitted when slicing or indexing
diff --git a/tests/codegen/issues/issue-98294-get-mut-copy-from-slice-opt.rs b/tests/codegen/issues/issue-98294-get-mut-copy-from-slice-opt.rs
index 9f65222b38697..40827e32a0124 100644
--- a/tests/codegen/issues/issue-98294-get-mut-copy-from-slice-opt.rs
+++ b/tests/codegen/issues/issue-98294-get-mut-copy-from-slice-opt.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: The debug assertions get in the way
 //@ compile-flags: -O
 
 #![crate_type = "lib"]
diff --git a/tests/codegen/iter-repeat-n-trivial-drop.rs b/tests/codegen/iter-repeat-n-trivial-drop.rs
index d0838a3e860d4..31020b77984ba 100644
--- a/tests/codegen/iter-repeat-n-trivial-drop.rs
+++ b/tests/codegen/iter-repeat-n-trivial-drop.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 #![feature(iter_repeat_n)]
diff --git a/tests/codegen/layout-size-checks.rs b/tests/codegen/layout-size-checks.rs
index 55c2e86b40bbd..901f8f822f320 100644
--- a/tests/codegen/layout-size-checks.rs
+++ b/tests/codegen/layout-size-checks.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/lib-optimizations/iter-sum.rs b/tests/codegen/lib-optimizations/iter-sum.rs
index 6b6d61a30660a..b563a6debb52b 100644
--- a/tests/codegen/lib-optimizations/iter-sum.rs
+++ b/tests/codegen/lib-optimizations/iter-sum.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: the debug assertions get in the way
 //@ compile-flags: -O
 //@ only-x86_64 (vectorization varies between architectures)
 #![crate_type = "lib"]
diff --git a/tests/codegen/mem-replace-big-type.rs b/tests/codegen/mem-replace-big-type.rs
index 0234b63aba5e1..c71cbbd08f9ac 100644
--- a/tests/codegen/mem-replace-big-type.rs
+++ b/tests/codegen/mem-replace-big-type.rs
@@ -4,7 +4,7 @@
 // known to be `1` after inlining).
 
 //@ compile-flags: -C no-prepopulate-passes -Zinline-mir=no
-//@ ignore-debug: the debug assertions get in the way
+//@ ignore-debug: precondition checks in ptr::read make them a bad candidate for MIR inlining
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/mem-replace-simple-type.rs b/tests/codegen/mem-replace-simple-type.rs
index b6885aad9e402..b00fbad05d9c5 100644
--- a/tests/codegen/mem-replace-simple-type.rs
+++ b/tests/codegen/mem-replace-simple-type.rs
@@ -1,6 +1,6 @@
 //@ compile-flags: -O -C no-prepopulate-passes
 //@ only-x86_64 (to not worry about usize differing)
-//@ ignore-debug (the debug assertions get in the way)
+//@ ignore-debug: precondition checks make mem::replace not a candidate for MIR inlining
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/ptr-arithmetic.rs b/tests/codegen/ptr-arithmetic.rs
index 3a8bfee84ecfb..6f115d33d8ddf 100644
--- a/tests/codegen/ptr-arithmetic.rs
+++ b/tests/codegen/ptr-arithmetic.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O -Z merge-functions=disabled
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/ptr-read-metadata.rs b/tests/codegen/ptr-read-metadata.rs
index 622a1cec4ac69..4c623dee5e1e9 100644
--- a/tests/codegen/ptr-read-metadata.rs
+++ b/tests/codegen/ptr-read-metadata.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O -Z merge-functions=disabled
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/simd/simd-wide-sum.rs b/tests/codegen/simd/simd-wide-sum.rs
index 010500139e595..2edee552ca69a 100644
--- a/tests/codegen/simd/simd-wide-sum.rs
+++ b/tests/codegen/simd/simd-wide-sum.rs
@@ -1,7 +1,6 @@
 //@ revisions: llvm mir-opt3
 //@ compile-flags: -C opt-level=3 -Z merge-functions=disabled --edition=2021
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 //@ [mir-opt3]compile-flags: -Zmir-opt-level=3
 //@ [mir-opt3]build-pass
 
diff --git a/tests/codegen/simd/swap-simd-types.rs b/tests/codegen/simd/swap-simd-types.rs
index e03e2d4ff8dfd..32e75220d696a 100644
--- a/tests/codegen/simd/swap-simd-types.rs
+++ b/tests/codegen/simd/swap-simd-types.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O -C target-feature=+avx
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/slice-as_chunks.rs b/tests/codegen/slice-as_chunks.rs
index c9cd482a9a4ea..631d18d780951 100644
--- a/tests/codegen/slice-as_chunks.rs
+++ b/tests/codegen/slice-as_chunks.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-64bit (because the LLVM type of i64 for usize shows up)
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 #![feature(slice_as_chunks)]
diff --git a/tests/codegen/slice-indexing.rs b/tests/codegen/slice-indexing.rs
index 52714a76a8dd2..ecce920107197 100644
--- a/tests/codegen/slice-indexing.rs
+++ b/tests/codegen/slice-indexing.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-64bit (because the LLVM type of i64 for usize shows up)
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/slice-iter-fold.rs b/tests/codegen/slice-iter-fold.rs
index 5a9d789b98464..1770cd4a11994 100644
--- a/tests/codegen/slice-iter-fold.rs
+++ b/tests/codegen/slice-iter-fold.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: the debug assertions get in the way
 //@ compile-flags: -O
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/slice-iter-len-eq-zero.rs b/tests/codegen/slice-iter-len-eq-zero.rs
index 43c64511e527b..b2a4b2495b6a2 100644
--- a/tests/codegen/slice-iter-len-eq-zero.rs
+++ b/tests/codegen/slice-iter-len-eq-zero.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions add extra comparisons
 #![crate_type = "lib"]
 
 type Demo = [u8; 3];
diff --git a/tests/codegen/slice-iter-nonnull.rs b/tests/codegen/slice-iter-nonnull.rs
index c82ae3b61b412..c960688b00c18 100644
--- a/tests/codegen/slice-iter-nonnull.rs
+++ b/tests/codegen/slice-iter-nonnull.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug (these add extra checks that make it hard to verify)
 #![crate_type = "lib"]
 #![feature(exact_size_is_empty)]
 
diff --git a/tests/codegen/slice-ref-equality.rs b/tests/codegen/slice-ref-equality.rs
index d34aecd1903a7..371e685ec6c92 100644
--- a/tests/codegen/slice-ref-equality.rs
+++ b/tests/codegen/slice-ref-equality.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O -Zmerge-functions=disabled
-//@ ignore-debug (the extra assertions get in the way)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/slice-reverse.rs b/tests/codegen/slice-reverse.rs
index 40bc89bc9d0cf..21add929f051f 100644
--- a/tests/codegen/slice-reverse.rs
+++ b/tests/codegen/slice-reverse.rs
@@ -1,6 +1,6 @@
 //@ compile-flags: -O
 //@ only-x86_64
-//@ ignore-debug: the debug assertions in from_raw_parts get in the way
+//@ ignore-debug: debug assertions prevent generating shufflevector
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/slice_as_from_ptr_range.rs b/tests/codegen/slice_as_from_ptr_range.rs
index cc811e8f5894c..47c60461c0e81 100644
--- a/tests/codegen/slice_as_from_ptr_range.rs
+++ b/tests/codegen/slice_as_from_ptr_range.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-64bit (because we're using [ui]size)
-//@ ignore-debug (because the assertions get in the way)
 
 #![crate_type = "lib"]
 #![feature(slice_from_ptr_range)]
diff --git a/tests/codegen/swap-large-types.rs b/tests/codegen/swap-large-types.rs
index 2069789081403..b182f3ed94798 100644
--- a/tests/codegen/swap-large-types.rs
+++ b/tests/codegen/swap-large-types.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/swap-small-types.rs b/tests/codegen/swap-small-types.rs
index 8d7f9f49eef64..5fdf4a5804a9c 100644
--- a/tests/codegen/swap-small-types.rs
+++ b/tests/codegen/swap-small-types.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O -Z merge-functions=disabled
 //@ only-x86_64
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/transmute-optimized.rs b/tests/codegen/transmute-optimized.rs
index 43d2a55c9955e..9217def76b519 100644
--- a/tests/codegen/transmute-optimized.rs
+++ b/tests/codegen/transmute-optimized.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O -Z merge-functions=disabled
-//@ ignore-debug
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/unchecked_shifts.rs b/tests/codegen/unchecked_shifts.rs
index 4e351d8d33356..9cf2f2b0cb673 100644
--- a/tests/codegen/unchecked_shifts.rs
+++ b/tests/codegen/unchecked_shifts.rs
@@ -1,5 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug (because unchecked is checked in debug)
 
 #![crate_type = "lib"]
 #![feature(unchecked_shifts)]
diff --git a/tests/codegen/unwind-landingpad-inline.rs b/tests/codegen/unwind-landingpad-inline.rs
index 953ba5e901a20..77ef8d2a5fe75 100644
--- a/tests/codegen/unwind-landingpad-inline.rs
+++ b/tests/codegen/unwind-landingpad-inline.rs
@@ -1,6 +1,5 @@
 //@ min-llvm-version: 17.0.2
 //@ compile-flags: -Copt-level=3
-//@ ignore-debug: the debug assertions get in the way
 #![crate_type = "lib"]
 
 // This test checks that we can inline drop_in_place in
diff --git a/tests/codegen/vec-calloc.rs b/tests/codegen/vec-calloc.rs
index bae344ab01d62..f88ed7ae8a555 100644
--- a/tests/codegen/vec-calloc.rs
+++ b/tests/codegen/vec-calloc.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -O -Z merge-functions=disabled
 //@ only-x86_64
-//@ ignore-debug
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vec-in-place.rs b/tests/codegen/vec-in-place.rs
index 3ac2ec13d4764..7a175dc4f7e1c 100644
--- a/tests/codegen/vec-in-place.rs
+++ b/tests/codegen/vec-in-place.rs
@@ -1,4 +1,4 @@
-//@ ignore-debug: the debug assertions get in the way
+//@ ignore-debug: FIXME: checks for call detect scoped noalias metadata
 //@ compile-flags: -O -Z merge-functions=disabled
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vec-iter-collect-len.rs b/tests/codegen/vec-iter-collect-len.rs
index 0c225abd326d8..e4242c5740239 100644
--- a/tests/codegen/vec-iter-collect-len.rs
+++ b/tests/codegen/vec-iter-collect-len.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: the debug assertions get in the way
 //@ compile-flags: -O
 #![crate_type="lib"]
 
diff --git a/tests/codegen/vec-iter.rs b/tests/codegen/vec-iter.rs
index 47e11af5bc3d1..310680969c4fe 100644
--- a/tests/codegen/vec-iter.rs
+++ b/tests/codegen/vec-iter.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: the debug assertions get in the way
 //@ compile-flags: -O
 #![crate_type = "lib"]
 #![feature(exact_size_is_empty)]
diff --git a/tests/codegen/vec-optimizes-away.rs b/tests/codegen/vec-optimizes-away.rs
index 9cbfbc115b046..77a94b0b4294a 100644
--- a/tests/codegen/vec-optimizes-away.rs
+++ b/tests/codegen/vec-optimizes-away.rs
@@ -1,4 +1,3 @@
-//@ ignore-debug: the debug assertions get in the way
 //@ compile-flags: -O
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vec-reserve-extend.rs b/tests/codegen/vec-reserve-extend.rs
index 12795937bc817..1f00f7d206339 100644
--- a/tests/codegen/vec-reserve-extend.rs
+++ b/tests/codegen/vec-reserve-extend.rs
@@ -1,6 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug
-// (with debug assertions turned on, `assert_unchecked` generates a real assertion)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vec-shrink-panik.rs b/tests/codegen/vec-shrink-panik.rs
index 33b70300bf415..4e996b234f98d 100644
--- a/tests/codegen/vec-shrink-panik.rs
+++ b/tests/codegen/vec-shrink-panik.rs
@@ -4,7 +4,7 @@
 //@ [old]ignore-llvm-version: 17 - 99
 //@ [new]min-llvm-version: 17
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
+//@ ignore-debug: plain old debug assertions
 //@ needs-unwind
 #![crate_type = "lib"]
 #![feature(shrink_to)]
diff --git a/tests/codegen/vec_pop_push_noop.rs b/tests/codegen/vec_pop_push_noop.rs
index 5a2009b01d7ce..83765d1085419 100644
--- a/tests/codegen/vec_pop_push_noop.rs
+++ b/tests/codegen/vec_pop_push_noop.rs
@@ -1,6 +1,4 @@
 //@ compile-flags: -O
-//@ ignore-debug
-// (with debug assertions turned on, `assert_unchecked` generates a real assertion)
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vecdeque-drain.rs b/tests/codegen/vecdeque-drain.rs
index cd549f8ebd4a6..31fcf035f1154 100644
--- a/tests/codegen/vecdeque-drain.rs
+++ b/tests/codegen/vecdeque-drain.rs
@@ -1,7 +1,7 @@
 // Check that draining at the front or back doesn't copy memory.
 
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
+//@ ignore-debug: FIXME: checks for call detect scoped noalias metadata
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vecdeque-nonempty-get-no-panic.rs b/tests/codegen/vecdeque-nonempty-get-no-panic.rs
index 1128b4ed7a442..3f802de9eeed7 100644
--- a/tests/codegen/vecdeque-nonempty-get-no-panic.rs
+++ b/tests/codegen/vecdeque-nonempty-get-no-panic.rs
@@ -1,7 +1,6 @@
 // Guards against regression for optimization discussed in issue #80836
 
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/vecdeque_no_panic.rs b/tests/codegen/vecdeque_no_panic.rs
index 57b6b2abbea9a..be2c4810ebc44 100644
--- a/tests/codegen/vecdeque_no_panic.rs
+++ b/tests/codegen/vecdeque_no_panic.rs
@@ -1,7 +1,7 @@
 // This test checks that `VecDeque::front[_mut]()` and `VecDeque::back[_mut]()` can't panic.
 
 //@ compile-flags: -O
-//@ ignore-debug: the debug assertions get in the way
+//@ ignore-debug: plain old debug assertions
 
 #![crate_type = "lib"]
 
diff --git a/tests/codegen/virtual-function-elimination.rs b/tests/codegen/virtual-function-elimination.rs
index bf4a74085ed80..6c391d9114b42 100644
--- a/tests/codegen/virtual-function-elimination.rs
+++ b/tests/codegen/virtual-function-elimination.rs
@@ -1,6 +1,5 @@
 //@ compile-flags: -Zvirtual-function-elimination -Clto -O -Csymbol-mangling-version=v0
 //@ ignore-32bit
-//@ ignore-debug
 
 // CHECK: @vtable.0 = {{.*}}, !type ![[TYPE0:[0-9]+]], !vcall_visibility ![[VCALL_VIS0:[0-9]+]]
 // CHECK: @vtable.1 = {{.*}}, !type ![[TYPE1:[0-9]+]], !vcall_visibility ![[VCALL_VIS0:[0-9]+]]
diff --git a/tests/mir-opt/pre-codegen/slice_filter.rs b/tests/mir-opt/pre-codegen/slice_filter.rs
index 45686f0bf8806..35881ff2b18c6 100644
--- a/tests/mir-opt/pre-codegen/slice_filter.rs
+++ b/tests/mir-opt/pre-codegen/slice_filter.rs
@@ -1,6 +1,5 @@
 // skip-filecheck
 //@ compile-flags: -O -Zmir-opt-level=2 -Cdebuginfo=2
-//@ ignore-debug: standard library debug assertions add a panic that breaks this optimization
 
 #![crate_type = "lib"]
 
diff --git a/tests/mir-opt/pre-codegen/slice_filter.variant_a-{closure#0}.PreCodegen.after.mir b/tests/mir-opt/pre-codegen/slice_filter.variant_a-{closure#0}.PreCodegen.after.mir
index 7370da5629c18..65cac0a81ef13 100644
--- a/tests/mir-opt/pre-codegen/slice_filter.variant_a-{closure#0}.PreCodegen.after.mir
+++ b/tests/mir-opt/pre-codegen/slice_filter.variant_a-{closure#0}.PreCodegen.after.mir
@@ -1,6 +1,6 @@
 // MIR for `variant_a::{closure#0}` after PreCodegen
 
-fn variant_a::{closure#0}(_1: &mut {closure@$DIR/slice_filter.rs:8:25: 8:39}, _2: &&(usize, usize, usize, usize)) -> bool {
+fn variant_a::{closure#0}(_1: &mut {closure@$DIR/slice_filter.rs:7:25: 7:39}, _2: &&(usize, usize, usize, usize)) -> bool {
     let mut _0: bool;
     let mut _3: &(usize, usize, usize, usize);
     let _4: &usize;
diff --git a/tests/mir-opt/pre-codegen/slice_filter.variant_b-{closure#0}.PreCodegen.after.mir b/tests/mir-opt/pre-codegen/slice_filter.variant_b-{closure#0}.PreCodegen.after.mir
index 5477796512c57..d9e118d879a6a 100644
--- a/tests/mir-opt/pre-codegen/slice_filter.variant_b-{closure#0}.PreCodegen.after.mir
+++ b/tests/mir-opt/pre-codegen/slice_filter.variant_b-{closure#0}.PreCodegen.after.mir
@@ -1,6 +1,6 @@
 // MIR for `variant_b::{closure#0}` after PreCodegen
 
-fn variant_b::{closure#0}(_1: &mut {closure@$DIR/slice_filter.rs:12:25: 12:41}, _2: &&(usize, usize, usize, usize)) -> bool {
+fn variant_b::{closure#0}(_1: &mut {closure@$DIR/slice_filter.rs:11:25: 11:41}, _2: &&(usize, usize, usize, usize)) -> bool {
     let mut _0: bool;
     let mut _3: &(usize, usize, usize, usize);
     let _4: usize;