diff --git a/src/ontology/ro-edit.owl b/src/ontology/ro-edit.owl
index d3492f9d..e453fc62 100644
--- a/src/ontology/ro-edit.owl
+++ b/src/ontology/ro-edit.owl
@@ -2921,7 +2921,6 @@ AnnotationAssertion(obo:IAO_0000115 obo:RO_0002333 "inverse of enables")
 AnnotationAssertion(obo:IAO_0000117 obo:RO_0002333 "Chris Mungall")
 AnnotationAssertion(rdfs:label obo:RO_0002333 "enabled by"@en)
 SubObjectPropertyOf(obo:RO_0002333 obo:RO_0002328)
-SubObjectPropertyOf(obo:RO_0002333 ObjectInverseOf(obo:RO_0002215))
 
 # Object Property: obo:RO_0002334 (regulated by)