diff --git a/lib/rustler_precompiled.ex b/lib/rustler_precompiled.ex
index 70dcb88..7b3ea27 100644
--- a/lib/rustler_precompiled.ex
+++ b/lib/rustler_precompiled.ex
@@ -557,7 +557,8 @@ defmodule RustlerPrecompiled do
         arch = normalize_arch(target_system.arch)
 
         vendor =
-          with vendor when vendor in ~w(pc redhat suse) <- target_system.vendor, do: "unknown"
+          with vendor when vendor in ~w(pc redhat suse alpine) <- target_system.vendor,
+               do: "unknown"
 
         %{target_system | arch: arch, vendor: vendor}
 
diff --git a/test/rustler_precompiled_test.exs b/test/rustler_precompiled_test.exs
index 9b72ea7..6e432ac 100644
--- a/test/rustler_precompiled_test.exs
+++ b/test/rustler_precompiled_test.exs
@@ -60,6 +60,19 @@ defmodule RustlerPrecompiledTest do
                RustlerPrecompiled.target(config, @available_targets, @available_nif_versions)
     end
 
+    test "x86_64 in a PC running Alpine Linux" do
+      target_system = %{arch: "x86_64", vendor: "alpine", os: "linux", abi: "musl"}
+
+      config = %{
+        target_system: target_system,
+        nif_version: "2.14",
+        os_type: {:unix, :linux}
+      }
+
+      assert {:ok, "nif-2.14-x86_64-unknown-linux-musl"} =
+               RustlerPrecompiled.target(config, @available_targets, @available_nif_versions)
+    end
+
     test "x86_64 or amd64 in a PC running Linux" do
       target_system = %{arch: "amd64", vendor: "pc", os: "linux", abi: "gnu"}