diff --git a/src/common.rs b/src/common.rs
index d39bf700035f9..de36d6ce44dc2 100644
--- a/src/common.rs
+++ b/src/common.rs
@@ -431,7 +431,11 @@ impl<'tcx> FunctionCx<'_, '_, 'tcx> {
 
     // Note: must be kept in sync with get_caller_location from cg_ssa
     pub(crate) fn get_caller_location(&mut self, mut source_info: mir::SourceInfo) -> CValue<'tcx> {
-        let span_to_caller_location = |fx: &mut FunctionCx<'_, '_, 'tcx>, span: Span| {
+        let span_to_caller_location = |fx: &mut FunctionCx<'_, '_, 'tcx>, mut span: Span| {
+            // Remove `Inlined` marks as they pollute `expansion_cause`.
+            while span.is_inlined() {
+                span.remove_mark();
+            }
             let topmost = span.ctxt().outer_expn().expansion_cause().unwrap_or(span);
             let caller = fx.tcx.sess.source_map().lookup_char_pos(topmost.lo());
             let const_loc = fx.tcx.const_caller_location((