diff --git a/Tools/clinic/clinic.py b/Tools/clinic/clinic.py
index 8353941f929eb1b..afbe0098d2024fc 100755
--- a/Tools/clinic/clinic.py
+++ b/Tools/clinic/clinic.py
@@ -67,7 +67,7 @@
 
 
 # match '#define Py_LIMITED_API'
-LIMITED_CAPI_REGEX = re.compile(r'#define +Py_LIMITED_API')
+LIMITED_CAPI_REGEX = re.compile(r'# *define +Py_LIMITED_API')
 
 
 class Sentinels(enum.Enum):