Addresses #2952 terminal bronchiole part of secondary pulmonary lobule #2953
Conversation
Addresses #2952 terminal bronchiole part of secondary pulmonary lobule
| @@ -43847,7 +43847,7 @@ property_value: structure_notes "lacks submucosa and cartilage plates; they have | |||
| [Term] | |||
| id: UBERON:0002187 | |||
| name: terminal bronchiole | |||
| def: "The last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls." [ISBN:0-397-51047-0, MGI:cwg, MP:0002268] | |||
| def: "A bronchiole that is part of a secondary pulmonary lobule and the last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls." [ISBN:0-397-51047-0, MGI:cwg, MP:0002268, PMID:16543587] | |||
There was a problem hiding this comment.
Given the ambiguity you detail in the linked issue, keeping the original definition (which doesn't seem contested) and using the relationship "overlaps" may be a less controversial solution. Will defer to @JoshuaFortriede or another SME for confirmation.
There was a problem hiding this comment.
Webb 2006 (paywall article) states:
Each secondary lobule is supplied by a small bronchiole
and Ohno 2021 states:
The secondary pulmonary lobule is supplied by a lobular bronchiole
These definitions match my understanding; that the primary bronchiole is the street into the neighborhood (secondary pulmonary lobule), and the terminal bronchioles are the main streets contained within that neighborhood. As such, I believe the new definition works.
I would also suggest adding that the terminal bronchiole is between the primary bronchiole and respiratory bronchiole. Specifically the terminal is distal to the primary, and proximal to the respiratory.
Here is my cheat sheet that I made to keep these airways/structures and space/segments together. The "Type" or RO might not be completely accurate.
There was a problem hiding this comment.
Thank you for your input and clarification, @JoshuaFortriede. The cheat sheet is very useful!
I would also suggest adding that the terminal bronchiole is between the primary bronchiole and respiratory bronchiole. Specifically the terminal is distal to the primary, and proximal to the respiratory.
In a different ticket #2957 I have already added 'terminal bronchiole' SubclassOf ' distally connected to' some 'respiratory bronchiole'. However, mice have none or few respiratory bronchioles, and therefore 'terminal bronchioles' are connected to alveolar ducts. Therefore I will have to revert that axiom in a different ticket. On the other side, the lobular bronchiole can be found between the primary bronchiole and the respiratory bronchiole. I would like to investigate a bit more before adding that axiom.
There was a problem hiding this comment.
Consider using singular form in the def:
A bronchiole that is part of a secondary pulmonary lobule and the last conducting structure of a non-respiratory bronchiole; after this point, the airways have alveoli in their walls.
| @@ -43862,6 +43862,7 @@ xref: SCTID:278981008 | |||
| xref: UMLS:C0225666 {source="ncithesaurus:Terminal_Bronchiole"} | |||
| xref: Wikipedia:Terminal_bronchiole | |||
| is_a: UBERON:0002186 ! bronchiole | |||
| relationship: part_of UBERON:0010369 ! secondary pulmonary lobule | |||
There was a problem hiding this comment.
Given Joshua's comment, I think part_of is ok
aleixpuigb
deleted the
2952_terminal_bronchiole-secondary_pulmonary_lobule
branch
Addresses #2952 terminal bronchiole part of secondary pulmonary lobule.
@JoshuaFortriede, as some of the information about it was a bit ambiguous (see ticket #2952), I would appreciate if you could confirm that this edits are appropriate? Thank you!